It's eradicated predominantly by hepatic metabolism (mostly CYP3A4) and is converted to an Lively metabolite with Homes just like the guardian, sildenafil. The two sildenafil along with the metabolite have terminal 50 % lives of about 4 several hours.
It’s not recognised what exactly might occur if a woman usually takes Viagra. Presently, you'll find mixed critiques about the effects on the drug in girls.
The security and efficacy of combinations of VIAGRA with other PDE5 Inhibitors, together with REVATIO or other pulmonary arterial hypertension (PAH) treatment options that contains sildenafil, or other therapies for erectile dysfunction have not been studied.
It truly is not possible to determine whether these events are connected directly to the usage of PDE5 inhibitors or to other factors [see ADVERSE REACTIONS].
For those who have questions on drug interactions which will have an affect on you, speak with your health practitioner or pharmacist.
A 25-mg starting dosage might also be advisable in case you’re 65 years or more mature. See “Dosage changes” just over for particulars about when a lessen dose could possibly be prescribed.
Usually do not acquire sildenafil if you are also employing a nitrate drug for upper body pain or coronary heart challenges, together with nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some leisure medicines for example "poppers". Using sildenafil with a nitrate drugs can cause a unexpected and major lessen in blood pressure level.
Alpha-blockers are occasionally prescribed for prostate difficulties or large blood pressure. In a few people, the usage of VIAGRA with alpha-blockers can cause a fall in blood pressure level or to fainting.
Simply call your physician without delay if you have an allergic response to Viagra. However, if you believe you’re aquiring a healthcare emergency, contact 911 or your neighborhood crisis selection.
The Unwanted side effects detailed beneath will not be knowledgeable by Everybody who usually takes this medication. In case you are worried about Uncomfortable side effects, go over the risks and great things about this medication using your medical doctor.
How often can I acquire Viagra? Am i able to choose it each day? Viagra need to only be taken as needed just before sexual activity. You will take it daily, if necessary.
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Your medical doctor could have proposed this medication for situations apart from These detailed in these drug info content articles.
If a dosage works very well but causes bothersome Negative effects, your medical doctor could advise a decreased dosage. If a dosage doesn’t perform to assist you to get or maintain an erection, your medical doctor may well boost your dosage.